The Last Panther is the queen of Wakanda in the 24th century, never named, who introduces herself by the title she carries: in her time, Wakanda has been destroyed by an alien invasion from the Horde, making her the last Black Panther her civilization will ever produce. She travels back to 1896 using advanced future technology, arriving in Ethiopia to intercept Kuda and Tafari after they retrieve the vibranium axe.

She proves a formidable combatant, requiring a concerted effort from both Wakandans to subdue her. Once restrained, she reveals herself as Wakandan and delivers her warning. Using her technology, she shares her memories of the future with them directly, letting them witness the ruins of the Golden City after the Horde's assault. The axe must be left where it was found so that it can eventually reach a museum and be retrieved by Killmonger, whose actions will ultimately push T'Challa to open Wakanda to the world, closing off the future she has come to prevent.

She is pulled back to her future while Kuda and Tafari complete her mission, facing a full assault by the Horde alongside her remaining Dora Milaje to hold the time portal open. To our knowledge, this was her final act.